Qualitative and quantitative comparison of the proteome of erythroid cells differentiated from human iPSCs and adult erythroid cells by multiplex TMT labelling and nanoLC-MS/MS.

Qualitative and quantitative comparison of the proteome of erythroid cells differentiated from human iPSCs and adult erythroid cells by multiplex TMT labelling and nanoLC-MS/MS.

Induced pluripotent stem cells (iPSC) are an attractive progenitor source for the generation of in vitro blood products. However, before iPSC-derived erythroid cells can be considered for therapeutic use their similarity to adult erythroid cells must be confirmed. We have analysed the proteome of er...

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Bibliographic Details
Main Authors: Kongtana Trakarnsanga, Marieangela C Wilson, Rebecca E Griffiths, Ashley M Toye, Lee Carpenter, Kate J Heesom, Steve F Parsons, David J Anstee, Jan Frayne
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4096399?pdf=render

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http://europepmc.org/articles/PMC4096399?pdf=render

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