The possible molecular mechanisms of farnesol on the antifungal resistance of C. albicans biofilms: the regulation of CYR1 and PDE2

Abstract Background Farnesol has potential antifungal activity against Candida albicans biofilms, but the molecular mechanism of this activity is still unclear. Farnesol inhibits hyphal growth by regulating the cyclic AMP (cAMP) signalling pathway in C. albicans, and CYR1 and PDE2 regulate a pair of...

Full description

Bibliographic Details
Main Authors: Shengyan Chen, Jinping Xia, Chengxi Li, Lulu Zuo, Xin Wei
Format: Article
Language:English
Published: BMC 2018-12-01
Series:BMC Microbiology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12866-018-1344-z