Genotypes of informative loci from 1000 Genomes data allude evolution and mixing of human populations

Abstract Principal Component Analysis (PCA) projects high-dimensional genotype data into a few components that discern populations. Ancestry Informative Markers (AIMs) are a small subset of SNPs capable of distinguishing populations. We integrate these two approaches by proposing an algorithm to ide...

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Bibliographic Details
Main Authors: Sridevi Padakanti, Khong-Loon Tiong, Yan-Bin Chen, Chen-Hsiang Yeang
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-97129-2