MMP-13 enzyme and pH responsive theranostic nanoplatform for osteoarthritis

Abstract Stimulus-responsive therapy permits precise control of therapeutic effect only at lesion of interest, which determines it a promising method for diagnosis and imaging-guided precision therapy. The acid environment and overexpressed matrix metalloproteinases-13 (MMP-13) are typical markers i...

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Bibliographic Details
Main Authors: Qiumei Lan, Rongbin Lu, Haimin Chen, Yunfen Pang, Feng Xiong, Chong Shen, Zainen Qin, Li Zheng, Guojie Xu, Jinmin Zhao
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Journal of Nanobiotechnology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12951-020-00666-7