Monocyte-derived tissue transglutaminase in multiple sclerosis patients: reflecting an anti-inflammatory status and function of the cells?

Monocyte-derived tissue transglutaminase in multiple sclerosis patients: reflecting an anti-inflammatory status and function of the cells?

Abstract Background Leukocyte infiltration into the central nervous system is an important feature of multiple sclerosis (MS) pathology. Among the infiltrating cells, monocytes comprise the largest population and are considered to play a dual role in the course of the disease. The enzyme tissue tran...

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Bibliographic Details
Main Authors: Claudia Sestito, John J. P. Brevé, Marja C. J. A. van Eggermond, Joep Killestein, Charlotte E. Teunissen, Joram van Rossum, Micha M. M. Wilhelmus, Benjamin Drukarch, Peter J. van den Elsen, Anne-Marie van Dam
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Journal of Neuroinflammation
Subjects:
Multiple sclerosis
Tissue transglutaminase
Inflammation
Human monocytes
Cytokine
Adhesion/migration
Online Access:http://link.springer.com/article/10.1186/s12974-017-1035-y

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http://link.springer.com/article/10.1186/s12974-017-1035-y

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