Reverse Genetic Approaches for the Generation of Full Length and Subgenomic Replicon of EV71 Virus

Enterovirus 71 (EV71) is a neurotropic pathogen that causes hand, foot, and mouth disease (HFMD) and it has been consistently associated with severe neurological, cardiac, and respiratory complications. Yet there is no specific treatment for this virus and we still know little about the viral pathog...

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Bibliographic Details
Main Authors: Hang Yang, Xiaohui Zhao, Meng Xun, Chaofeng Ma, Hongliang Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Microbiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.665879/full