Prediction of Protein Hotspots from Whole Protein Sequences by a Random Projection Ensemble System

Hotspot residues are important in the determination of protein-protein interactions, and they always perform specific functions in biological processes. The determination of hotspot residues is by the commonly-used method of alanine scanning mutagenesis experiments, which is always costly and time c...

Full description

Bibliographic Details
Main Authors: Jinjian Jiang, Nian Wang, Peng Chen, Chunhou Zheng, Bing Wang
Format: Article
Language:English
Published: MDPI AG 2017-07-01
Series:International Journal of Molecular Sciences
Subjects:
IBk
Online Access:https://www.mdpi.com/1422-0067/18/7/1543