Ultrafast Comparison of Personal Genomes via Precomputed Genome Fingerprints

Ultrafast Comparison of Personal Genomes via Precomputed Genome Fingerprints

We present an ultrafast method for comparing personal genomes. We transform the standard genome representation (lists of variants relative to a reference) into “genome fingerprints” via locality sensitive hashing. The resulting genome fingerprints can be meaningfully compared even when the input dat...

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Bibliographic Details
Main Authors: Gustavo Glusman, Denise E. Mauldin, Leroy E. Hood, Max Robinson
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Genetics
Subjects:
computational genomics
algorithms
genome comparison
study design
population genetics
privacy
Online Access:http://journal.frontiersin.org/article/10.3389/fgene.2017.00136/full

Internet

http://journal.frontiersin.org/article/10.3389/fgene.2017.00136/full

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