HNF1α and SREBP2 are important regulators of NPC1L1 in human liver

HNF1α and SREBP2 are important regulators of NPC1L1 in human liver

Niemann-Pick C1-like 1 (NPC1L1), a key regulator of intestinal cholesterol absorption, is highly expressed in human liver. Here, we aimed to gain more insight into mechanisms participating in its hepatic regulation in humans. Correlation analysis in livers from Chinese patients with and without gall...

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Bibliographic Details
Main Authors: Camilla Pramfalk, Zhao-Yan Jiang, Qu Cai, Hai Hu, Sheng-Dao Zhang, Tian-Quan Han, Mats Eriksson, Paolo Parini
Format: Article
Language:English
Published: Elsevier 2010-06-01
Series:Journal of Lipid Research
Subjects:
Niemann-Pick C1-like 1
sterol regulatory element binding protein 2
hepatic nuclear factor
cotransfection
chromatin immunoprecipitation
correlation analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520410090

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http://www.sciencedirect.com/science/article/pii/S0022227520410090

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