Advanced glycation end products potentiate the stimulatory effect of glucose on macrophage lipoprotein lipase expression

Lipoprotein lipase (LPL) secreted by macrophages in the arterial wall promotes atherosclerosis. We have shown that macrophages of patients with type 2 diabetes overproduce LPL and that metabolic factors, including glucose, stimulate macrophage LPL secretion. In this study, we determined the effect o...

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Bibliographic Details
Main Authors: Marie-Claude Beauchamp, Sophie-Élise Michaud, Ling Li, Maryam Radimeh Sartippour, Geneviève Renier
Format: Article
Language:English
Published: Elsevier 2004-09-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752031292X