Flavonoids activate endothelial nitric oxide synthase by altering their phosphorylation via mitogen-activated protein kinase pathways in glucose-induced endothelial cells

Flavonoids activate endothelial nitric oxide synthase by altering their phosphorylation via mitogen-activated protein kinase pathways in glucose-induced endothelial cells

Specific mechanisms underlying cardioprotective and anti-inflammatory effects of flavonoids remain unclear. The effects of two flavonoids—hesperidin and naringin—on endothelial nitric oxide synthase (eNOS) induction in human umbilical vein endothelial cells (HUVECs) were investigated here, and possi...

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Bibliographic Details
Main Authors: Chae Eun Kim, Seongho Han, Moo Hyun Kim, Sung-Whan Kim
Format: Article
Language:English
Published: Elsevier 2015-08-01
Series:Journal of Functional Foods
Subjects:
Flavonoid
eNOS
endothelial cell
MAPK signalling pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464615003321

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http://www.sciencedirect.com/science/article/pii/S1756464615003321

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