Cten is targeted by Kras signalling to regulate cell motility in the colon and pancreas.

Cten is targeted by Kras signalling to regulate cell motility in the colon and pancreas.

CTEN/TNS4 is an oncogene in colorectal cancer (CRC) which enhances cell motility although the mechanism of Cten regulation is unknown. We found an association between high Cten expression and KRAS/BRAF mutation in a series of CRC cell lines (p = 0.03) and hypothesised that Kras may regulate Cten. To...

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Bibliographic Details
Main Authors: Saleh Al-Ghamdi, Abdulkader Albasri, Julien Cachat, Salih Ibrahem, Belal A Muhammad, Darryl Jackson, Abdolrahman S Nateri, Karin B Kindle, Mohammad Ilyas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3116852?pdf=render

Internet

http://europepmc.org/articles/PMC3116852?pdf=render

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