Extra-virgin olive oil phenols hydroxytyrosol and hydroxytyrosol acetate, down-regulate the production of mediators involved in joint erosion in human synovial cells

Extra-virgin olive oil phenols hydroxytyrosol and hydroxytyrosol acetate, down-regulate the production of mediators involved in joint erosion in human synovial cells

The hallmark of rheumatoid arthritis (RA) pathology is characterized by both hyperproliferation of synovial fibroblasts (SFs) and massive infiltration of inflammatory immune cells. This study was conducted to evaluate the efficacy of hydroxytyrosol (HTy) and hydroxytyrosol-acetate (HTy-Ac) in regula...

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Bibliographic Details
Main Authors: María Ángeles Rosillo, Marina Sánchez-Hidalgo, María Luisa Castejón, Tatiana Montoya, Alejandro González-Benjumea, José G. Fernández-Bolaños, Catalina Alarcón-de-la-Lastra
Format: Article
Language:English
Published: Elsevier 2017-09-01
Series:Journal of Functional Foods
Subjects:
EVOO
Inflammatory response
Olive oil
Rheumatoid arthritis
Synovial fibroblasts
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464617303584

Internet

http://www.sciencedirect.com/science/article/pii/S1756464617303584

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