Genomic epidemiology of artemisinin resistant malaria
The current epidemic of artemisinin resistant Plasmodium falciparum in Southeast Asia is the result of a soft selective sweep involving at least 20 independent kelch13 mutations. In a large global survey, we find that kelch13 mutations which cause resistance in Southeast Asia are present at low freq...
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Format: | Article |
Language: | English |
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eLife Sciences Publications Ltd
2016-03-01
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Series: | eLife |
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Online Access: | https://elifesciences.org/articles/08714 |