Identification of highly conserved putative developmental enhancers bound by SOX3 in neural progenitors using ChIP-Seq.

The transcription factor SOX3 is expressed within most neural progenitor (NP) cells of the vertebrate central nervous system (CNS) and is essential for normal brain development in mice and humans. However, despite the widespread expression of Sox3, CNS defects in null mice are relatively mild due to...

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Bibliographic Details
Main Authors: Dale McAninch, Paul Thomas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4237438?pdf=render