The NLRP3 Inflammasome: Role and Therapeutic Potential in Pain Treatment

Pain is a fundamental feature of inflammation. The immune system plays a critical role in the activation of sensory neurons and there is increasing evidence of neuro-inflammatory mechanisms contributing to painful pathologies. The inflammasomes are signaling multiprotein complexes that are key compo...

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Bibliographic Details
Main Authors: Hana Starobova, Evelyn Israel Nadar, Irina Vetter
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Physiology
Subjects:
NOD
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2020.01016/full