A novel membrane sensor controls the localization and ArfGEF activity of bacterial RalF.

The intracellular bacterial pathogen Legionella pneumophila (Lp) evades destruction in macrophages by camouflaging in a specialized organelle, the Legionella-containing vacuole (LCV), where it replicates. The LCV maturates by incorporating ER vesicles, which are diverted by effectors that Lp injects...

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Bibliographic Details
Main Authors: Marcia Folly-Klan, Eric Alix, Danièle Stalder, Pampa Ray, Lionel V Duarte, Anna Delprato, Mahel Zeghouf, Bruno Antonny, Valérie Campanacci, Craig R Roy, Jacqueline Cherfils
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24244168/pdf/?tool=EBI