Selenium Dioxide Induced Apoptosis in Cervical Cancer Cells via Regulating Apoptosis-related Let-7a MicroRNA and Proteins

Aim: To investigate the effects of selenium dioxide (SeO2) on the apoptosis and the involved epigenetic mechanisms in two cervical cancer cell lines. Methods: Human cervical carcinoma cell lines HeLa and CaSki were treated with 1.875–30 µmol/L SeO2 for 24 h. Morphological changes were observed by op...

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Bibliographic Details
Main Authors: Sisun Liu, Jieqi Xiong, Ling Guo, Min Xiu, Feng He, Yuanlei Lou, Fei Guo
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-01-01
Series:Cancer Translational Medicine
Subjects:
p53
Online Access:http://www.cancertm.com/article.asp?issn=2395-3977;year=2015;volume=1;issue=6;spage=188;epage=195;aulast=Liu