Predictive value of interferon-lambda gene polymorphisms for treatment response in chronic hepatitis C.

Predictive value of interferon-lambda gene polymorphisms for treatment response in chronic hepatitis C.

BACKGROUND:IL28B gene polymorphism is the best baseline predictor of response to interferon alfa-based antiviral therapies in chronic hepatitis C. Recently, a new IFN-L4 polymorphism was identified as first potential functional variant for induction of IL28B expression. Individualization of interfer...

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Bibliographic Details
Main Authors: Simone Susser, Eva Herrmann, Christian Lange, Nabila Hamdi, Tobias Müller, Thomas Berg, Dany Perner, Stefan Zeuzem, Christoph Sarrazin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4231027?pdf=render

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http://europepmc.org/articles/PMC4231027?pdf=render

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