Influence of exogenous growth hormone administration on circulating concentrations of α-klotho in healthy and chronic kidney disease subjects: a prospective, single-center open case-control pilot study

Influence of exogenous growth hormone administration on circulating concentrations of α-klotho in healthy and chronic kidney disease subjects: a prospective, single-center open case-control pilot study

Abstract Background The CKD-associated decline in soluble α-Klotho (α-Klotho) levels is considered detrimental. Some studies suggest a direct induction of α-Klotho concentrations by growth hormone (GH). In the present study, the effect of exogenous GH administration on α-Klotho concentrations in a c...

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Bibliographic Details
Main Authors: Aaltje Y. Adema, Camiel L. M. de Roij van Zuijdewijn, Joost G. Hoenderop, Martin H. de Borst, Piet M. Ter Wee, Annemieke C. Heijboer, Marc G. Vervloet, for the NIGRAM consortium
Format: Article
Language:English
Published: BMC 2018-11-01
Series:BMC Nephrology
Subjects:
α-Klotho
Growth hormone
Chronic kidney disease
Online Access:http://link.springer.com/article/10.1186/s12882-018-1114-z

Internet

http://link.springer.com/article/10.1186/s12882-018-1114-z

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