Autocrine Human Urotensin II Enhances Macrophage-Derived Foam Cell Formation in Transgenic Rabbits

Circulating urotensin II (UII) is involved in the development of atherosclerosis. However, the role of autocrine UII in the development of atherosclerosis remains unclear. Here, we tested the hypothesis that autocrine UII would promote atherosclerosis. Transgenic rabbits were created as a model to s...

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Bibliographic Details
Main Authors: Sihai Zhao, Yafeng Li, Shoucui Gao, Xiaojing Wang, Lijing Sun, Daxing Cheng, Liang Bai, Hua Guan, Rong Wang, Jianglin Fan, Enqi Liu
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2015/843959