Chitosan-Alginate Nanoparticle System Efficiently Delivers Doxorubicin to MCF-7 Cells

A chitosan-alginate nanoparticle system encapsulating doxorubicin (DOX) was prepared by a novel ionic gelation method using alginate as the crosslinker. These nanoparticles were around 100 nm in size and more stable with higher positive zeta potential and had higher % encapsulation efficiency (95%)...

Full description

Bibliographic Details
Main Authors: Nuwanthi P. Katuwavila, A. D. L. Chandani Perera, Sameera R. Samarakoon, Preethi Soysa, Veranja Karunaratne, Gehan A. J. Amaratunga, D. Nedra Karunaratne
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Journal of Nanomaterials
Online Access:http://dx.doi.org/10.1155/2016/3178904