Regulation of Endoplasmic Reticulum-Associated Protein Degradation (ERAD) by Ubiquitin

Quality control of protein folding inside the endoplasmic reticulum (ER) includes chaperone-mediated assistance in folding and the selective targeting of terminally misfolded species to a pathway called ER-associated protein degradation, or simply ERAD. Once selected for ERAD, substrates will be tra...

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Bibliographic Details
Main Authors: Leticia Lemus, Veit Goder
Format: Article
Language:English
Published: MDPI AG 2014-08-01
Series:Cells
Subjects:
p97
Online Access:http://www.mdpi.com/2073-4409/3/3/824