Modulation of the CD95-induced apoptosis: the role of CD95 N-glycosylation.

Protein modifications of death receptor pathways play a central role in the regulation of apoptosis. It has been demonstrated that O-glycosylation of TRAIL-receptor (R) is essential for sensitivity and resistance towards TRAIL-mediated apoptosis. In this study we ask whether and how glycosylation of...

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Bibliographic Details
Main Authors: Olga M Shatnyeva, Andriy V Kubarenko, Claudia E M Weber, Alexander Pappa, Reinhard Schwartz-Albiez, Alexander N R Weber, Peter H Krammer, Inna N Lavrik
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3097226?pdf=render