Pretargeted imaging and radioimmunotherapy of cancer using antibodies and bioorthogonal chemistry
Selective delivery of radionuclides to tumors may be accomplished using a two-step approach, in which in the first step the tumor is pretargeted with an unlabeled antibody construct and in the second step the tumor is targeted with a radiolabeled small molecule. This results in a more rapid clearanc...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2014-11-01
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| Series: | Frontiers in Medicine |
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| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fmed.2014.00044/full |