Spontaneous Up states in vitro: a single-metric index of the functional maturation and regional differentiation of the cerebral cortex

Understanding the development and differentiation of the neocortex remains a central focus of neuroscience. While previous studies have examined isolated aspects of cellular and synaptic organization, an integrated functional index of the cortical microcircuit is still lacking. Here we aimed to prov...

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Bibliographic Details
Main Authors: Pavlos eRigas, Dimitrios A. Adamos, Charalambos eSigalas, Panagiotis eTsakanikas, Nikolaos A. Laskaris, Irini eSkaliora
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-10-01
Series:Frontiers in Neural Circuits
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncir.2015.00059/full