In silico and in vitro studies on the protein-protein interactions between Brugia malayi immunomodulatory protein calreticulin and human C1q.

Filarial parasites modulate effective immune response of their host by releasing a variety of immunomodulatory molecules, which help in the long persistence of the parasite within the host. The present study was aimed to characterize an immunomodulatory protein of Brugia malayi and its interaction w...

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Bibliographic Details
Main Authors: Sunita Yadav, Smita Gupta, Chandrabose Selvaraj, Pawan Kumar Doharey, Anita Verma, Sanjeev Kumar Singh, Jitendra Kumar Saxena
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4153637?pdf=render