Direct observation of selective autophagy induction in cells and tissues by self-assembled chiral nanodevice

Chiral assemblies have gained great interest for probing intracellular effects. Here, the authors report on the development of an upconversion nanoparticle-centred yolk-shell nanoparticle tetrahedron for the induction of autophagy and the monitoring of ATP levels both in living cells and in vivo.

Bibliographic Details
Main Authors: Maozhong Sun, Tiantian Hao, Xiaoyun Li, Aihua Qu, Liguang Xu, Changlong Hao, Chuanlai Xu, Hua Kuang
Format: Article
Language:English
Published: Nature Publishing Group 2018-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-06946-z