Trans-active factors controlling the IL-2 gene in adult human T-cell subsets

IL-2 secretion in total or subsets of PHA/PMA-stimulated PBMC-derived human T-lymphocytes was monitored and found to be largely due to CD4+CD8− cells. The presence and functional state of transcription factors (TF) was assessed by protein-DNA interaction assays and functional transactivation experim...

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Bibliographic Details
Main Authors: A. Mouzaki, R. H. Zubler, A. Doucet, D. Rungger
Format: Article
Language:English
Published: Hindawi Limited 1992-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/S0962935192000073