Prophylactic Treatment of Probiotic and Metformin Mitigates Ethanol-Induced Intestinal Barrier Injury: In Vitro, In Vivo, and In Silico Approaches

Ethanol depletes intestinal integrity and promotes gut dysbiosis. Studies have suggested the individual role of probiotics and metformin Met in protecting intestinal barrier function from injuries induced by ethanol. The objective of the current study is to investigate the potential mechanism by whi...

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Bibliographic Details
Main Authors: Farhin Patel, Kirti Parwani, Priyashi Rao, Dhara Patel, Rakesh Rawal, Palash Mandal
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2021/5245197