Dopamine D1/D5, but not D2/D3, receptor dependency of synaptic plasticity at hippocampal mossy fiber synapses that is enabled by patterned afferent stimulation, or spatial learning

Although the mossy fiber (MF) synapses of the hippocampal CA3 region display quite distinct properties in terms of the molecular mechanisms that underlie synaptic plasticity, they nonetheless exhibit persistent (>24h) synaptic plasticity that is akin to that observed at the Schaffer collateral (S...

Full description

Bibliographic Details
Main Authors: Hardy Hagena, Denise Manahan-Vaughan
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-09-01
Series:Frontiers in Synaptic Neuroscience
Subjects:
CA3
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnsyn.2016.00031/full