Low spontaneous apoptosis index at diagnosis predicts a high-risk phenotype in paediatric acute lymphoblastic leukaemia

Low spontaneous apoptosis index at diagnosis predicts a high-risk phenotype in paediatric acute lymphoblastic leukaemia

Background & objectives: Significance of apoptosis as a prognostic marker is less well studied in paediatric acute lymphoblastic leukaemia (ALL) cases. Hence, a prospective study, involving 30 paediatric ALL cases, was done to assess the clinical relevance of in vivo apoptosis. Methods: Peripher...

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Bibliographic Details
Main Authors: Ankita Singh, Prateek Bhatia, Amita Trehan, Deepak Bansal, Ajit Singh, Alka Bhatia
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:Indian Journal of Medical Research
Subjects:
Acute lymphoblastic leukaemia - apoptotic index - Bax/Bcl2 ratio - paediatric - ratio - spontaneous apoptosis - treatment
Online Access:http://www.ijmr.org.in/article.asp?issn=0971-5916;year=2018;volume=147;issue=3;spage=248;epage=255;aulast=Singh

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http://www.ijmr.org.in/article.asp?issn=0971-5916;year=2018;volume=147;issue=3;spage=248;epage=255;aulast=Singh

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