Efficient Synthesis of New Fluorinated β-Amino Acid Enantiomers through Lipase-Catalyzed Hydrolysis

An efficient and novel enzymatic method has been developed for the synthesis of β-fluorophenyl-substituted β-amino acid enantiomers through lipase PSIM (<i>Burkholderia cepasia</i>) catalyzed hydrolysis of racemic β-amino carboxylic ester hydrochloride salts <b>3a</b>–<b&g...

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Bibliographic Details
Main Authors: Sayeh Shahmohammadi, Ferenc Fülöp, Enikő Forró
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/25/24/5990