Selective Limbic Blood–Brain Barrier Breakdown in a Feline Model of Limbic Encephalitis with LGI1 Antibodies

Selective Limbic Blood–Brain Barrier Breakdown in a Feline Model of Limbic Encephalitis with LGI1 Antibodies

Human leucine-rich glioma-inactivated protein 1 encephalitis (LGI1) is an autoimmune limbic encephalitis in which serum and cerebrospinal fluid contain antibodies targeting LGI1, a protein of the voltage gated potassium channel (VGKC) complex. Recently, we showed that a feline model of limbic enceph...

Full description

Bibliographic Details
Main Authors: Anna R. Tröscher, Andrea Klang, Maria French, Lucía Quemada-Garrido, Sibylle Maria Kneissl, Christian G. Bien, Ákos Pákozdy, Jan Bauer
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-10-01
Series:Frontiers in Immunology
Subjects:
hippocampus
amygdala
tight junctions
limbic encephalitis
neuroinflammation
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01364/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01364/full

Similar Items