Pharmacotherapy of Insomnia with Ramelteon: Safety, Efficacy and Clinical Applications
Ramelteon is a tricyclic synthetic analog of melatonin that acts specifically on MT 1 and MT 2 melatonin receptors. Ramelteon is the first melatonin receptor agonist approved by the Food and Drug Administration (FDA) for the treatment of insomnia characterized by sleep onset difficulties. Ramelteon...
Main Authors: | Seithikurippu R. Pandi-Perumal, D. Warren Spence, Joris C. Verster, Venkatramanujam Srinivasan, Gregory M. Brown, Daniel P. Cardinali, Rüdiger Hardeland |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2011-01-01
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Series: | Journal of Central Nervous System Disease |
Online Access: | https://doi.org/10.4137/JCNSD.S1611 |
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