Pharmacotherapy of Insomnia with Ramelteon: Safety, Efficacy and Clinical Applications

Ramelteon is a tricyclic synthetic analog of melatonin that acts specifically on MT 1 and MT 2 melatonin receptors. Ramelteon is the first melatonin receptor agonist approved by the Food and Drug Administration (FDA) for the treatment of insomnia characterized by sleep onset difficulties. Ramelteon...

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Bibliographic Details
Main Authors: Seithikurippu R. Pandi-Perumal, D. Warren Spence, Joris C. Verster, Venkatramanujam Srinivasan, Gregory M. Brown, Daniel P. Cardinali, Rüdiger Hardeland
Format: Article
Language:English
Published: SAGE Publishing 2011-01-01
Series:Journal of Central Nervous System Disease
Online Access:https://doi.org/10.4137/JCNSD.S1611