Oral immunization with a novel attenuated Salmonella Typhimurium encoding influenza HA, M2e and NA antigens protects chickens against H7N9 infection

Abstract Attenuated Salmonella strains constitute a promising technology for the development of efficient protein-based influenza vaccines. H7N9, a low pathogenic avian influenza (LPAI) virus, is a major public health concern and currently there are no effective vaccines against this subtype. Herein...

Full description

Bibliographic Details
Main Authors: Je Hyoung Kim, Irshad Ahmed Hajam, John Hwa Lee
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Veterinary Research
Online Access:http://link.springer.com/article/10.1186/s13567-018-0509-y