Mg2+ Extrusion from Intestinal Epithelia by CNNM Proteins Is Essential for Gonadogenesis via AMPK-TORC1 Signaling in Caenorhabditis elegans.

Mg2+ Extrusion from Intestinal Epithelia by CNNM Proteins Is Essential for Gonadogenesis via AMPK-TORC1 Signaling in Caenorhabditis elegans.

Mg2+ serves as an essential cofactor for numerous enzymes and its levels are tightly regulated by various Mg2+ transporters. Here, we analyzed Caenorhabditis elegans strains carrying mutations in genes encoding cyclin M (CNNM) Mg2+ transporters. We isolated inactivating mutants for each of the five...

Full description

Bibliographic Details
Main Authors: Tasuku Ishii, Yosuke Funato, Osamu Hashizume, Daisuke Yamazaki, Yusuke Hirata, Kiyoji Nishiwaki, Nozomu Kono, Hiroyuki Arai, Hiroaki Miki
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-08-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC5001713?pdf=render

Internet

http://europepmc.org/articles/PMC5001713?pdf=render

Similar Items