Targeted Expansion of Tissue-Resident CD8+ T Cells to Boost Cellular Immunity in the Skin

Summary: Tissue-resident memory (TRM) CD8+ T cells are positioned within environmental barrier tissues to provide a first line of defense against pathogen entry, but whether these specialized T cell populations can be readily boosted to increase protective immunity is ill defined. Here, we demonstra...

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Bibliographic Details
Main Authors: Samuel J. Hobbs, Jeffrey C. Nolz
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719314597