AMPKα1-Sensitivity of Orai1 and Ca2+ Entry in T - Lymphocytes

AMPKα1-Sensitivity of Orai1 and Ca2+ Entry in T - Lymphocytes

Background/Aims: T-lymphocyte activation and function critically depends on Ca2+ signaling, which is regulated by store operated Ca2+ entry (SOCE). Human and mouse T lymphocytes express AMP activated kinase AMPKα1, which is rapidly activated following elevation of cytosolic Ca2+ concentration ([Ca2+...

Full description

Bibliographic Details
Main Authors: Shefalee K. Bhavsar, Sebastian Schmidt, Diwakar Bobbala, Meerim K. Nurbaeva, Zohreh Hosseinzadeh, Katja Merches, Abul Fajol, Jan Wilmes, Florian Lang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2013-09-01
Series:Cellular Physiology and Biochemistry
Subjects:
AMP-activated protein kinase
Calcium
Orai1
T lymphocytes
Online Access:http://www.karger.com/Article/FullText/354472

Internet

http://www.karger.com/Article/FullText/354472

Similar Items