Norepinephrine enhances the LPS-induced expression of COX-2 and secretion of PGE<sub>2 </sub>in primary rat microglia

<p>Abstract</p> <p>Background</p> <p>Recent studies suggest an important role for neurotransmitters as modulators of inflammation. Neuroinflammatory mediators such as cytokines and molecules of the arachidonic acid pathway are generated and released by microglia. The mo...

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Bibliographic Details
Main Authors: Candelario-Jalil Eduardo, de Oliveira Antonio CP, Haake Elisabeth, Fiebich Bernd L, Schlachetzki Johannes CM, Heneka Michael T, Hüll Michael
Format: Article
Language:English
Published: BMC 2010-01-01
Series:Journal of Neuroinflammation
Online Access:http://www.jneuroinflammation.com/content/7/1/2