Autophagy activation and enhanced mitophagy characterize the Purkinje cells of <it>pcd </it>mice prior to neuronal death

<p>Abstract</p> <p>Purkinje cells are a class of specialized neurons in the cerebellum, and are among the most metabolically active of all neurons, as they receive immense synaptic stimulation, and provide the only efferent output from the cerebellum. Degeneration of Purkinje cells...

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Bibliographic Details
Main Authors: Chakrabarti Lisa, Eng Jeremiah, Ivanov Nishi, Garden Gwenn A, La Spada Albert R
Format: Article
Language:English
Published: BMC 2009-07-01
Series:Molecular Brain
Online Access:http://www.molecularbrain.com/content/2/1/24