Membrane-enriched proteome changes and prion protein expression during neural differentiation and in neuroblastoma cells

Membrane-enriched proteome changes and prion protein expression during neural differentiation and in neuroblastoma cells

Abstract Background The function of the prion protein, involved in the so-called prion diseases, remains a subject of intense debate and the possibility that it works as a pleiotropic protein through the interaction with multiple membrane proteins is somehow supported by recent reports. Therefore, t...

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Bibliographic Details
Main Authors: J. A. Macedo, D. Schrama, I. Duarte, E. Tavares, J. Renaut, M. E. Futschik, P. M. Rodrigues, E. P. Melo
Format: Article
Language:English
Published: BMC 2017-04-01
Series:BMC Genomics
Subjects:
Prion protein
2D-DIGE
Neural differentiation
Chaperone activity
Redox homeostasis
Online Access:http://link.springer.com/article/10.1186/s12864-017-3694-6

Internet

http://link.springer.com/article/10.1186/s12864-017-3694-6

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