Lactoferrin deficiency promotes colitis-associated colorectal dysplasia in mice.

Nonresolving inflammatory processes affect all stages of carcinogenesis. Lactoferrin, a member of the transferrin family, is involved in the innate immune response and anti-inflammatory, anti-microbial, and anti-tumor activities. We previously found that lactoferrin is significantly down-regulated i...

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Main Authors: Qiurong Ye, Ying Zheng, Songqing Fan, Zailong Qin, Nan Li, Anliu Tang, Feiyan Ai, Xuemei Zhang, Yanhui Bian, Wei Dang, Jing Huang, Ming Zhou, Yanhong Zhou, Wei Xiong, Qun Yan, Jian Ma, Guiyuan Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4110006?pdf=render