Establishment of Leptin-Responsive Cell Lines from Adult Mouse Hypothalamus.

Leptin resistance is considered to be the primary cause of obesity. However, the cause of leptin resistance remains incompletely understood, and there is currently no cure for the leptin-resistant state. In order to identify novel drug-target molecules that could overcome leptin resistance, it would...

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Bibliographic Details
Main Authors: Hiroshi Iwakura, Katsuko Dote, Mika Bando, Hiroyuki Koyama, Kiminori Hosoda, Kenji Kangawa, Kazuwa Nakao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4744015?pdf=render