Adolescent Isolation Interacts With DISC1 Point Mutation to Impair Adult Social Memory and Synaptic Functions in the Hippocampus

Adolescent Isolation Interacts With DISC1 Point Mutation to Impair Adult Social Memory and Synaptic Functions in the Hippocampus

Disrupted-in-schizophrenia 1 (DISC1) is a strong candidate susceptibility gene for a spectrum of neuropsychiatric diseases including schizophrenia, bipolar disorder and major depression, all of which are thought to result from interactions between gene mutations and environmental risk factors such a...

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Bibliographic Details
Main Authors: Nan Li, Lin Cui, Ge Song, Li Guo, Huating Gu, Haisheng Cao, Guo-Dong Li, Yu Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Cellular Neuroscience
Subjects:
DISC1
L100P
social interaction
social memory
adolescent stress
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2018.00238/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2018.00238/full

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