Genetic Analysis of Multiple Myeloma Identifies Cytogenetic Alterations Implicated in Disease Complexity and Progression

Genetic Analysis of Multiple Myeloma Identifies Cytogenetic Alterations Implicated in Disease Complexity and Progression

Multiple myeloma (MM) is a genetically heterogeneous disease characterized by genomic chaos making it difficult to distinguish driver from passenger mutations. In this study, we integrated data from whole genome gene expression profiling (GEP) microarrays and CytoScan HD high-resolution genomic arra...

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Bibliographic Details
Main Authors: Can Li, Erik B. Wendlandt, Benjamin Darbro, Hongwei Xu, Gregory S. Thomas, Guido Tricot, Fangping Chen, John D. Shaughnessy, Fenghuang Zhan
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Cancers
Subjects:
multiple myeloma
copy number variations
gene expression profiles
cytogenetics
protein network signatures
Online Access:https://www.mdpi.com/2072-6694/13/3/517

Internet

https://www.mdpi.com/2072-6694/13/3/517

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