Effects of geldanamycin on neurite outgrowth-related proteins and kinases in nerve growth factor-differentiated pheochromocytoma 12 cells

Heat shock protein 90 (HSP90) antagonists are currently being evaluated as potential anticancer drugs. However, adverse effects related to these drugs, such as fatigue and pain, suggest that they affect neurons. Therefore, to understand the influence of HSP90 inhibitors on neurons, we investigated t...

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Bibliographic Details
Main Authors: Keisuke Migita, Taichi Matsumoto, Kazuki Terada, Kazuhiko Ono, Shuji Hara
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319356919