Exogenous Antioxidants—Double-Edged Swords in Cellular Redox State: Health Beneficial Effects at Physiologic Doses versus Deleterious Effects at High Doses

The balance between oxidation and antioxidation is believed to be critical in maintaining healthy biological systems. Under physiological conditions, the human antioxidative defense system including e.g., superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), glutathione (GSH) and...

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Bibliographic Details
Main Authors: Jaouad Bouayed, Torsten Bohn
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.4161/oxim.3.4.12858