Angiopoietin-like 7 is an anti-angiogenic protein required to prevent vascularization of the cornea.

We sought to identify the anti-angiogenic molecule expressed in corneal keratocytes that is responsible for maintaining the avascularity of the cornea.Human umbilical vein endothelial cells (HUVECs) were cultured with either human dermal fibroblasts or with human corneal keratocytes under serum-free...

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Bibliographic Details
Main Authors: Tetsuya Toyono, Tomohiko Usui, Seiichi Yokoo, Yukako Taketani, Suguru Nakagawa, Masahiko Kuroda, Satoru Yamagami, Shiro Amano
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4306551?pdf=render